PI


Kiyoung Park, Ph. D.

Academic Career
    Assistant professor
            Department of Chemistry, Korea Advanced Institute of Science and Technology, 2014 ~
    Postdoctoral research fellow
            Department of Chemistry, Stanford University, 2010 ~ 2014 (Advisor: Prof. Edward Solomon)
    Research assistant
            Department of Chemistry, University of Wisconsin-Madison, 2006 ~ 2010 (Advisor: Prof. Thomas Brunold)
    Teaching assistant
            Department of Chemistry, University of Wisconsin-Madison, 2005 ~ 2006

Education
    Ph. D. in Physical Chemistry, University of Wisconsin-Madison, 2010 (Advisor: Prof. Thomas Brunold)
    B. S. in Chemistry, Seoul National University, 2004

Publications
"Resonance Rama spectroscopic study of the interaction between co(II)rrinoids and the ATP:corrinoid adenosyltransferase PduO from Lactobacillus reuteri"
Kiyoung Park*,  Paola E. Mera, Jorge C. Escalante-Semerena, Thomas C. Brunold*
J. Bio. Inorg. Chem. In press. doi:10.1007/s00775-016-1371-x

"Structure/function correlations over binuclear non-heme iron active sites"
Edward I Solomon*, Kiyoung Park
J. Bio. Inorg. Chem. In press. doi:10.1007/s00775-016-1372-9

“Unprecedented mechanism employed by the Salmonella enterica EutT ATP:Co(I)rrinoid adenosyltransferase precludes adenosylation of incomplete Co(II)rrinoids”
Kiyoung Park, Paola E. Mera, Theodore. C. Moore, Jorge C. Escalante-Semerena, Thomas C. Brunold* 
Angew. Chem. Int. Ed., 2015, 54, 7158-7161.


“Modeling nuclear resonance vibrational spectroscopic data of binuclear nonheme iron enzymes using density functional theory” 

Kiyoung Park, Edward I. Solomon* 

Can. J. Chem. 2014, 92, 975-978.


"Nuclear Resonance Vibrational Spectroscopic and Computational Study
of High-valent Diiron Complexes Relevant to Enzyme Intermediates"
Kiyoung Park, Caleb B. Bell III, Lei V. Liu, Dong Wang, Genqiang Xue, Yeonju Kwak, Shaun D. Wong, Kenneth M. Light, Jiyong Zhao, E. Ercan Alp, Yoshitaka Yoda, Makina Saito, Yasuhiro Kobayashi, Takehiro Ohta, Makoto Seto, Larry Que, Jr., and Edward I. Solomon*
Proc. Natl. Acad. Sci. USA, 2013, 110, 6275-6280.
 
"Nuclear Resonance Vibrational Spectroscopy and DFT Study of Peroxo-bridged Biferric Complexes: Structural Insight   into Peroxy Intermediates of Binuclear Non-heme Iron Enzymes"
Kiyoung Park, Tomohiro Tsugawa, Hideki Furutachi, Yeonju Kwak, Lei V. Liu, Shaun D. Wong, Yoshitaka Yoda, Yasuhiro Kobayashi, Makina Saito, Masayuki Kurokuzu, Makoto Seto, Masatatsu Suzuki, and Edward I. Solomon*
Angew. Chem. Int. Ed. 2013, 52, 1294-1298.

"Resonance Raman and Computational Studies of B12 cofactors"
Kiyoung Park and Thomas C. Brunold*
J. Phys. Chem. B, 2013, 117, 5397-5410.

"Elucidation of the Iron(IV)–oxo Intermediate in the Non-Haem Iron Halogenase SyrB2"
S. D. Wong, M. Srnec, M. L. Matthews, L. V. Liu, Y. Kwak, K. Park, C. B. Bell, E. E. Alp, J. Zhao, Y. Yoda, S. Kitao, M. Seto, C. Krebs, J. M. Bollinger, E. I. Solomon*
Nature, 2013, 499, 320-323.

"Geometric and Electronic Structure of the MnIVFeIII Cofactor in Class Ic Ribonucleotide Reductase: Correlation to the Class Ia Binuclear Non-Heme Iron Enzymes"
Y. Kwak, W. Jiang, L. M. K. Dassama, K. Park, C. B. Bell, L. V. Liu, S. D. Wong, M. Saito, Y. Kobayashi, S. Kitao, M. Seto, Y. Yoda, E. E. Alp, J. Zhao, K. Crebs, J. M. Bollinger, E. I. Solomon*
J. Am. Chem. Soc. 2013, 135, 17573-17584.
  
"Spectroscopic Characterization of Active-Site Variants of the PduO-type ATP:Corrinoid Adenosyltransferase from Lactobacillus reuteri: Insights into the Mechanism of Four-Coordinate Co(II)corrinoid Formation"
Kiyoung Park, Paola E. Mera, Jorge C. Escalante-Semerena, and Thomas C. Brunold*
Inorg. Chem. 2012, 51, 4482-4494.
 
"Spectroscopically validated density functional theory studies of the B12 cofactors and their interactions with enzyme active sites"
Thomas C. Brunold,* Karen S. Conrad, Matthew D. Liptak, Kiyoung Park
Coord. Chem. Rev. 2009, 253, 779-794.
 
"Kinetic and Spectroscopic Studies of the ATP:Corrinoid Adenosyltransferase PduO from Lactobacillus reuteri: Substrate Specificity and Insights into the Mechanism of Co(II)corrinoid Reduction"
Kiyoung Park, Paola E. Mera, Jorge C. Escalante-Semerena, and Thomas C. Brunold*
Biochemistry 2008, 47, 9007-9015.
 
"Structural Characterization of a Human-Type Corrinoid Adenosyltransferase Confirms That Coenzyme B12 Is Synthesized through a Four-Coordinate Intermediate"
Martin St. Maurice, Paola E. Mera, Kiyoung Park, Thomas C. Brunold, Jorge C. Escalante-Semerena, and Ivan Rayment*
Biochemistry 2008, 47, 5755-5766.